Frederick sanger wife

Frederick sanger discovery of insulin
Frederick sanger insulin
What did frederick sanger discover

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Nobel Prize in Chemistry 1958 for his work on the structure of proteins, especially that of insulin.

Nobel Prize in Chemistry 1980 for contributions concerning the determination of base sequences in nucleic acids, shared with Walter Gilbert and Paul Berg.

Department of Biochemistry Part I student (1936-1939), Part II student (1939-1940), PhD student (1940-1943, PhD awarded 1943), Postdoctoral Researcher (1943-1951) and Medical Research Council External Scientific Staff (1951-1962).

Frederick Sanger took Part II Biochemistry at Cambridge, before starting a PhD in 1940 under the supervision of Norman "Bill" Pirie. Pirie, however, shortly moved to the Rothamsted Experimental Station in Harpenden to pursue his interest in viruses, and so Albert Neuberger became Sanger's supervisor for a project on the metabolism of the amino acid lysine. After obtaining his PhD in 1943 Sanger worked with the newly appointed Head of Department, Charles Chibnall, whose previous work on bovine insulin lead to Sanger determining the complete amino acid sequence of its two polypeptide chains. To this en

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Frederick Sanger

British biochemist (1918–2013)

Frederick SangerOM CH CBE FRS FAA (; 13 August 1918 – 19 November 2013) was a British biochemist who received the Nobel Prize in Chemistry twice.

He won the 1958 Chemistry Prize for determining the amino acid sequence of insulin and numerous other proteins, demonstrating in the process that each had a unique, definite structure; this was a foundational discovery for the central dogma of molecular biology.

At the newly constructed Laboratory of Molecular Biology in Cambridge, he developed and subsequently refined the first-ever DNA sequencing technique, which vastly expanded the number of feasible experiments in molecular biology and remains in widespread use today. The breakthrough earned him the 1980 Nobel Prize in Chemistry, which he shared with Walter Gilbert and Paul Berg.

He is one of only three people to have won multiple Nobel Prizes in the same category (the others being John Bardeen in physics and Karl Barry Sharpless in chemistry),^[5] and one of five persons with two Nobel Prizes.

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ProfessorFrederickSanger

Born13th August, 1918 (Gloucestershire, England, United Kingdom) - Died19th November, 2013 (Cambridge)

The first to determine the amino acid sequence of insulin, Sanger proved proteins have a defined chemical composition. He was also pivotal to the development of the dideoxy chain-termination method for sequencing DNA molecules, known as the Sanger method. This provided a breakthrough in the sequencing of long stretches of DNA in terms of speed and accuracy and laid the foundation for the Human Genome Project.

Fred Sanger in his laboratory at the Laboratory of Molecular Biology, c. 1969. (Photo credit: MRC, Laboratory of Molecilar Biology)

Family

Fred Sanger was the middle son of three children. His father, Frederick, started his work life as an Anglican medical missionary in China, but poor health forced him back to England where he took up a position as a general medical practitioner. Sanger's father converted to Quakerism soon after Fred's birth and raised the children as Quakers. Although Sanger's mother, Cicely (neé Crewdso